Tylenol Cold + Flu Severe Day/Night Caplets provide temporary relief of cold and flu symptoms. The daytime caplets are formulated to loosen phlegm and temporarily relieve symptoms such as headache, sore throat, nasal congestion and cough. The Nighttime caplets help relieve runny nose and sneezing along with other symptoms such as headache, cough, sore throat, nasal congestion, sinus congestion and pressure. Both formulas also temporarily reduce fever, for relief any time of the day.