Mucinex Instasoothe Sore Throat + Soothing Comfort medicated throat drops have a powerful 3 in 1 formula that relieves, soothes, and numbs sore throats. These honey & echinacea flavored sore throat lozenges provide rapid relief that lasts up to 2 hours. The active ingredient Hexylresorcinol, an oral pain reliever, provides powerful sore throat relief without menthol. Each medicated drop has less than 10 calories and 2.5g of sugar (no artificial sweeteners).